{"id":862,"date":"2025-09-15T23:03:25","date_gmt":"2025-09-15T15:03:25","guid":{"rendered":"https:\/\/www.anrim.cn\/?post_type=solution&#038;p=862"},"modified":"2025-09-29T12:56:32","modified_gmt":"2025-09-29T04:56:32","slug":"uniqueknock","status":"publish","type":"solution","link":"https:\/\/www.anrim.cn\/en\/solution\/uniqueknock\/","title":{"rendered":"UniqueKNOCK\u00ae"},"content":{"rendered":"<p>The UniqueKNOCK\u00ae kit is designed to overcome challenges associated with conventional transfection methods, such as low efficiency and high cytotoxicity. Specifically engineered for highly efficient and precise siRNA delivery and gene knockdown, it has evolved from a laboratory tool into a clinical-grade solution, providing a one-stop platform for gene silencing in scientific research and drug development. Using nano-needle delivery, siRNA is directly transported into the cytoplasm through nanoscale needle-like structures, effectively bypassing the toxicity of chemical transfection reagents and endosomal escape issues.<\/p>","protected":false},"excerpt":{"rendered":"<p>Addressing the low efficiency and high toxicity of traditional transfection methods, this technology is designed for efficient and precise siRNA delivery and gene knockout, providing a one-stop gene silencing solution for research and drug development.<\/p>","protected":false},"featured_media":909,"template":"","meta":{"_acf_changed":false},"solution_cat":[19],"class_list":["post-862","solution","type-solution","status-publish","has-post-thumbnail","hentry","solution_cat-intracellular-delivery-nanobiochip"],"blocksy_meta":[],"acf":[],"_links":{"self":[{"href":"https:\/\/www.anrim.cn\/en\/wp-json\/wp\/v2\/solution\/862","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.anrim.cn\/en\/wp-json\/wp\/v2\/solution"}],"about":[{"href":"https:\/\/www.anrim.cn\/en\/wp-json\/wp\/v2\/types\/solution"}],"version-history":[{"count":9,"href":"https:\/\/www.anrim.cn\/en\/wp-json\/wp\/v2\/solution\/862\/revisions"}],"predecessor-version":[{"id":1560,"href":"https:\/\/www.anrim.cn\/en\/wp-json\/wp\/v2\/solution\/862\/revisions\/1560"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.anrim.cn\/en\/wp-json\/wp\/v2\/media\/909"}],"wp:attachment":[{"href":"https:\/\/www.anrim.cn\/en\/wp-json\/wp\/v2\/media?parent=862"}],"wp:term":[{"taxonomy":"solution_cat","embeddable":true,"href":"https:\/\/www.anrim.cn\/en\/wp-json\/wp\/v2\/solution_cat?post=862"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}